29 September 2015Sportivo Luqueño – Deportes Tolima
Referee: Julio Bascuñan (CHI, photo)
Assistant Referee 1: Marcelo Barraza (CHI)
Assistant Referee 2: Jose Retamal (CHI)
Fourth Official: Ulises Mereles (PAR)
Referee Observer: Manuel Bernal (PAR)
Santa Fe – Emelec
Referee: Dario Ubriaco (URU)
Assistant Referee 1: Mauricio Espinosa (URU)
Assistant Referee 2: Richard Trinidad (URU)
Fourth Official: Wilson Lamouroux (COL)
Referee Observer: Pablo Montoya (COL)
30 September 2015
LDU Quito – River Plate
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Christian De La Cruz (COL)
Assistant Referee 2: Rafael Rivas (COL)
Fourth Official: Vinicio Espinel (ECU)
Referee Observer: Jose Carpio (ECU)
Olimpia – Independiente
Referee: Daniel Fedorczuk (URU)
Assistant Referee 1: Carlos Pastorino (URU)
Assistant Referee 2: Nicolas Taran (URU)
Fourth Official: Mario Diaz de Vivar (PAR)
Referee Observer: Ubaldo Aquino (PAR)
Brasília – Atlético Paranaense
Referee: Silvio Trucco (ARG)
Assistant Referee 1: Ivan Nuñez (ARG)
Assistant Referee 2: Christian Navarro (ARG)
Fourth Official: Dewson Freitas (BRA)
Referee Observer: Antonio Pereira (BRA)
Huracán – Sport Recife
Referee: Julio Quintana (PAR)
Assistant Referee 1: Rodney Aquino (PAR)
Assistant Referee 2: Carlos Cáceres (PAR)
Fourth Official: Pablo Diaz (ARG)
Referee Observer: Miguel Scime (ARG)
1 October 2015
Defensor Sporting – Lanús
Referee: Enrique Osses (CHI)
Assistant Referee 1: Christian Schiemann (CHI)
Assistant Referee 2: Claudio Rios (CHI)
Fourth Official: Andrés Cunha (URU)
Referee Observer: Juan Cardellino (URU)
Chapecoense – Libertad
Referee: Diego Haro (PER)
Assistant Referee 1: Raul Lopez (PER)
Assistant Referee 2: Victor Raez (PER)
Fourth Official: Anderson Daronco (BRA)
Referee Observer: Nilson Monção (BRA)
